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Pathology Testing

 

Pathology Definition

 

“The scientific study of the nature of disease and its causes, processes, development, and consequences.”

 

Haematology

 

"Haematology is the branch of medicine concerned with the nature, function and diseases of the blood. It covers the cellular and serum composition of the blood, the coagulation process, blood cell formation, haemoglobin synthesis and disorders of all of these."

 

SHLS’s laboratory in Abergavenny offers a wide range of tests that measure various elements in the blood, including white blood cells (WBC), red blood cells (RBC) and platelets. Results from a Full Blood Count can indicate conditions such as anaemia, bacterial or viral infection and blood clotting disorders. A typical Full Blood Count analysis will include the following:-

 

  • Haemoglobin
  • RBC
  • WBC
  • Mean Cell Volume
  • Mean Cell Haemoglobin
  • Mean Cell Haemoglobin Concentration
  • Platelets
  • Differential Count
  • Blood film can be added if appropriate

 

Biochemistry

 

"Biochemistry is the study of the chemical processes in living organisms and deals with the structure and function of cellular components such as proteins, carbohydrates, lipids, nucleic acids and other biomolecules."

 

Test Tubes

SHLS helps to keep people healthy and in work by offering an extensive range of tests for monitoring these chemical substances to ensure a healthy process and therefore a healthy person. Profiles are often requested as part of routine medicals, pre-employment screening and screening for visa and emigration purposes: below are some typically requested biochemistry profiles which can include a Full Blood Count:-

 

  • Urea & Creatinine (kidney function)
  • Liver Function Tests: Gamma GT, AST, ALT, ALP, TP, Albumin & Globulin
  • Glucose (checking for diabetes)
  • Full Lipid Profile: Cholesterol, High Density Lipoprotein (HDLP),Low DensityLipoprotein (LDL), Triglyceride
  • Prostate Specific Antigen testing (PSA) Total and Free

  • Thyroid function testing – TSH leading to Free T4 and Free T3 as appropriate

 

A further addition of CDT (Carbohydrate Deficient Transferrin) to this profile is often requested as an indictor of long term alcohol consumption. Profiles can be created to your company’s specific needs and can be incorporated into your personalised request form to make requesting such a test easy.

 

Microbiology

 

"Microbiology is the branch of biology that deals with the study of micro-organisms and their effects on other living organisms. Medical Microbiology is both a branch of medicine and Microbiology which deals with the study of micro-organisms including bacteria, viruses, fungi and parasites which are of medical importance and are capable of causing diseases in human beings."

 

Agar Dish

The microbiology department covers a range of areas, including bacteriology, mycology, and parasitological and involves the culture of various clinical and non-clinical samples to look for the presence of pathogenic organisms. In particular, SHLS offers both rapid PCR and culture screening for the detection of MRSA and, in doing so, are able to support both private and NHS hospitals in their battle for control of infection.

 

  • Food handler screening
  • Faeces culture and sensitivity
  • Urine culture and sensitivity
  • Faeces for ova, cysts and parasites
  • Faecal occult blood
  • Chlamydia – male and female
  • Pregnancy testing

 

Virology and Blood Borne Viruses

 

"Virology is the branch of medical science that studies viruses and viral diseases."

 

Blood-borne viruses (BBVs) are carried in blood but can also be found in urine, saliva, sputum and sweat (although minimal risk). The main BBVs of concern are Hepatitis B, C and HIV and our screening service includes post vaccination screening for Hepatitis to check immunity levels, Hepatitis B surface antigen screening to check for current or recent infection and Hepatitis B core antibody screening to look for past infection.

 

Other examples of virology tests available to establish any need for vaccination are:-

 

  • Hepatitis A
  • Rubella
  • Measles
  • Mumps
  • Varicella zoster (chicken pox)
  • Syphilis

 

Biological Monitoring

 

To check the efficacy of PPE and working environments when using potentially toxic substances and compliance with Health and Safety Regulations eg CLAW (Control of lead at work).

 

  • Lead -  Blood (for inorganic lead)and urine (for organic lead)
  • Zinc protoporphyrin – ZPP. Long term lead exposure
  • Isocyanates in urine – special container with preservative required, available from laboratory.
  • Polyaromatic hydrocarbons (PAH)
  • SPMA for benzene
  • Urine and blood metals
  • PCB

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Pathology Analyses


SHLS undertake various types of laboratory testing, offering a comprehensive amount of Pathology tests including Rapid MRSA.